POLYDIOXANONE monofilament synthetic absorbable suture is prepared from the polyester, poly (p-dioxanone). The empirical molecular formula of the polymer is Polydioxanone polymer has been found to be non-antigenic and elicits only a slight tissue reaction during absorption. Demetech Polydioxanone sutures meet the requirement of the current edition of the United States Pharmacopeia.
POLYDIOXANONE monofilament synthetic absorbable sutures are indicated for use in general soft tissue approximation, including use in pediatric cardiovascular tissue where growth is expected to occur and ophthalmic surgery
Two important characteristics describe the in vivo performance of absorbable sutures: first, tensile strength retention, and second, the absorption rate (loss of mass). POLYDIOXANONE synthetic absorbable suture has been formulated to minimize the variability of these characteristics and to provide wound support through an extended healing period. Data obtained from implantation studies show that the absorption of these sutures is minimal until about the 90th post-implantation day. Absorption is essentially complete within 180-220 days.
DemeTech's Polydioxanone suture is an absorbable, sterile, surgical suture composed of the polyester, poly(pdioxanone). DemeTech's Polydioxanone has been found to be nonantigenic and elicits only minimal tissue reactivity during the absorption process. Clinical trials have shown that after two weeks, approximately 75-80% of DemeTech's Polydioxanone initial strength remained. At four weeks, approximately 65-70% of DemeTech's Polydioxanone initial strength remained. At six weeks, approximately 55-60% remained. Complete absorption of DemeTech's Polydioxanone is 180-220 days.